2023
Jeong HC, Shukla S, Fok W, Huynh TN, Batista LF*, Parker RR* (*co-correspondent authors). USB1 is a miRNA deadenylase that regulates hematopoietic development. Science (2023). Open access through this link
2022
Batista LF*, Dokal I* and Parker RR* (*co-correspondent authors). Telomere Biology Disorders. Trends in Molecular Medicine (2022). Pubmed.
2021
Vessoni AT, Zhang T, Quinet A, Jeong HC, Munroe M, Wood M, Tedone E, Vindigni A, Shay JW, Greenberg RA, Batista LF. Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe. Journal of Cell Biology (2021). Pubmed
2020
Munroe M, Niero EL, Fok WC, Vessoni AT, Jeong HC, Brenner KA and Batista LF. telomere dysfunction activates p53 and represses HNF4a expression leading to impaired human hepatocyte development and function. Hepatology (2020). Pubmed
Shukla S, Jeong HC, Sturgeon M, Parker R* and Batista LF* (*co-correspondent authors). Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita. Blood Advances (2020). Pubmed
Vessoni AT, Filippi-Chiela EC, Lenz G and Batista LF. Tumor propagating cells: drivers of tumor plasticity, heterogeneity, and recurrence. Oncogene (2020). Pubmed
Quinet A, Tirman S, Jackson J, Šviković S, Lemaçon D, Carvajal-Maldonado D, González-Acosta D, Vessoni AT, Cybulla E, Wood M, Tavis S, Batista LF, Méndez J, Sale JE and Vindigni A. PRIMPOL-mediated adaptative response suppresses replication fork reversal in BRCA-deficient cells. Molecular Cell (2020). Pubmed
2019 – 2015
Fok WC, Shukla S, Vessoni AT, Brenner KA, Parker R, Sturgeon CM and Batista LF. Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita. Blood (2019). Pubmed
Brestoff JR, Vessoni AT, Brenner KA, et al. Acute graft-versus-host disease following lung transplantation in a patient with a novel TERT mutation. Thorax (2018). Pubmed
Fok WC, Niero EL, Dege C, Brenner KA, Sturgeon CM* and Batista LF* (*co-correspondent authors). p53 mediates failure of human definitive hematopoiesis in dyskeratosis congenita. Stem Cell Reports (2017). Pubmed
Fok WC and Batista LF. Stressed ends: telomere attrition in chronic diseases. Rev Bras Hematology (2017). Pubmed
Huh CJ, Zhang B, Victor MB, Dahiya S, Batista LF, Horvath S and Yoo AS. Maintenance of Age in Human Neurons Generated by MicroRNA-based Neuronal Conversion of Fibroblasts. eLIFE (2016). Pubmed
2014 – 2009
Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O’Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, Brunet A, Sage J and Wernig M. Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis. Cell Stem Cell (2014). Pubmed
Batista LF and Artandi SE. Understanding telomere diseases through analysis of patient-derived iPS cells. Current Opinion in Genetics & Development (2013). Pubmed
Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE. TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends. Cell (2012). Pubmed
Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera R and Artandi SE. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature (2011). Pubmed
Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Dahlborg EJ, Ramirez CL, Reyon D, Batista LF, Artandi SE, Wernig M & Joung JK. In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases. Stem Cells (2011). Pubmed
Batista LF and Artandi SE. Telomere uncapping, chromosomes, and carcinomas. Cancer Cell (2009). Pubmed
Saffi J, Agnoletto MH, Guecheva TN, Batista LF, Carvalho H, Henriques JA, Stary A, Menck CF, Sarasin A. Effect of the anti-neoplastic drug doxorubicin on XPD-mutated DNA repair-deficient human cells. DNA Repair (2010). Pubmed
Arruda-Neto JD, Friedberg EC, Bittencourt-Oliveira MC, Segreto HR, Moron MM, Maria DA, Batista LF, Schenberg AC. The role played by endogenous and exogenous electric fields in DNA signaling and repair. DNA Repair (2010). Pubmed
Batista LF, Kaina B and Menck CFM. How DNA lesions are turned into powerful killing structures: insights on UV-induced apoptosis. Mutation Research – Reviews (2009). Pubmed
Batista LF, Roos WP, Kaina B and Menck CFM. p53 mutant human glioma cells are sensitive to UV-C induced apoptosis due to impaired CPD removal. Molecular Cancer Research (2009). Pubmed
2008 – 2001
Batista LF, Roos WP, Christmann M, Menck CFM and Kaina B. Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2 and DNA double-strand breaks. Cancer Research (2007). Pubmed
Roos WP, Batista LF, Naumman SC, Wick W, Weller M, Menck CFM and Kaina B. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6- methylguanine. Oncogene (2007). Pubmed
Batista LF, Chiganças V, Brummati G, Amarante-Mendes GP and Menck CFM. Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells. Apoptosis (2006). Pubmed
Chiganças V, Batista LF, Brummati G, Amarante-Mentes GP, Yasui A and Menck CFM. Photorepair of RNA polymerase arrest and apoptosis after ultraviolet irradiation in normal and XPB deficient rodent cells. Cell Death & Differentiation (2002). Pubmed