Samajdar A, Amato R, Jo S, Cordes E, Tai A, Raffa DD, Batista LFZ (2026). Genes & Development.
Exosome Mediated Decay of Unstable Long Extended Precursors of Human Telomerase RNA is Dependent on 5`- Cap Trimethylation
DeSouza PA, Ishahak M, Qu X, McCornack C, Annamalai D, Mao DD, Vangipurapu R, Fu Y, Vessoni AT, Cleary RT, Han RH, Augsornworawat P, Woodiwiss T, Agovino D, Sizemore B, Kline J, Borhani-Haghighi M, Chen H, Pugazenthi S, Yano H, Wang T, Batista LFZ, Millman JR, Kim AH (2025). Nature communications, 17(1), 31.
INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model
Mendoza-Castrejon J, Yang W, Denby ED, Wang HC, Casey EB, Muthukumar R, Patel RM, Yoon J, Li Y, White JM, Chen R, Batista LFZ, Magee JA (2025). Blood.
Fetal context conveys heritable protection against MLL-rearranged AML that depends on MLL3
Camacho V, Bekendam R, Stone AP, Barrachina MN, Branfield S, Carminita E, Becker IC, Lee DH, Walsey E, Payne C, Kaplan JP, Tilburg J, Pal S, Batista LFZ, Italiano JE Jr, Machlus KR (2025). (Epub ahead of print). Blood Adv.
Induction of Moderate DNA Damage Enhances Megakaryopoiesis and Platelet Production
Raj IX, Koh WK, Harrison J, Zhang CR, Soares B, Krishnan A, Bjeije H, Parsons TM, Han W, Young A, Wang T, Batista LF, Challen GA. (2025). Cell Stem Cell, 32(8), 1251-1266.
Dnmt3a Controls Hematopoietic Stem Cells via DNA Methylation-Independent Regulation of Telomeres
Collins TB, Laranjeira ABA, Kong T, Fulbright MC, Fisher DAC, Sturgeon CM, Batista LFZ, Oh ST (2024). Exp Hematol, 132, 104178.
Altered erythropoiesis via JAK2 and ASXL1 mutations in myeloproliferative neoplasms
Jeong HC, Shukla S, Fok WC, Huynh TN, Batista LFZ*, Parker R* (*Co-Corresponding Author) (2023). Science, 379 (6635), 901-907.
USB1 is a miRNA deadenylase that regulates hematopoietic development
Vessoni AT, Zhang T, Quinet A, Jeong HC, Munroe M, Wood M, Tedone E, Vindigni A, Shay JW, Greenberg RA, Batista LFZ (2021). J Cell Biol, 220(6).
Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe
Munroe M, Niero EL, Fok WC, Vessoni AT, Jeong HC, Brenner KA, Batista LFZ (2020). Hepatology, 72(4), 1412-1429.
Telomere Dysfunction Activates p53 and Represses HNF4α Expression Leading to Impaired Human Hepatocyte Development and Function
Shukla S, Jeong HC, Sturgeon CM, Parker R, Batista LFZ (2020). Blood Adv, 4 (12), 2717-2722.
Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita
Quinet A, Tirman S, Jackson J, Šviković S, Lemaçon D, Carvajal-Maldonado D, González-Acosta D, Vessoni AT, Cybulla E, Wood M, Tavis S, Batista LFZ, Méndez J, Sale JE, Vindigni A (2020). Mol Cell, 77(3), 461-474.e9.
PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
Fok WC, Shukla S, Vessoni AT, Brenner KA, Parker R, Sturgeon CM, Batista LFZ (2019). Blood, 133(12), 1308-1312.
Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita
Brestoff JR, Vessoni AT, Brenner KA, Uy GL, DiPersio JF, Blinder M, Witt CA, Byers DE, Hachem RR, Truclock EP, Early DS, Anadkat MJ, Musiek A, Javidan-Nejad C, Balfe DM, Rosman IS, Liu C, Zhang L, Despotis GJ, Ruzinova MB, Sehn JK, Amarillo I, Heusel JW, Swat W, Kim BS, Wartman LD, Yusen RD, Batista LFZ (2018). Thorax, 73(5), 489-492.
Acute graft-versus-host disease following lung transplantation in a patient with a novel TERT mutation
Kreienkamp R, Graziano S, Coll-Bonfill N, Bedia-Diaz G, Cybulla E, Vindigni A, Dorsett D, Kubben N, Batista LFZ, Gonzalo S (2018). Cell Rep, 22(8), 2006-2015.
A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin
Fok WC, Niero ELO, Dege C, Brenner KA, Sturgeon CM*, Batista LFZ* (*Co-Corresponding Author) (2017). Stem Cell Reports, 9(2), 409-418.
p53 Mediates Failure of Human Definitive Hematopoiesis in Dyskeratosis Congenita
Fok WC, Batista LFZ (2017). Rev Bras Hematol Hemoter, 39(2), 98-99.
Stressed ends: telomere attrition in chronic diseases
Huh CJ, Zhang B, Victor MB, Dahiya S, Batista LF, Horvath S, Yoo AS (2016). Elife, 5.
Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts
Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O’Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, Brunet A, Sage J, Wernig M (2015). Cell Stem Cell, 16(1), 39-50.
Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis
Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE (2012). Cell, 150(3), 481-94.
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.
Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK (2011). Stem Cells, 29(11), 1717-26.
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases
Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE (2011). Nature, 474(7351), 399-402.
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
Saffi J, Agnoletto MH, Guecheva TN, Batista LF, Carvalho H, Henriques JA, Stary A, Menck CF, Sarasin A (2010). DNA Repair (Amst), 9(1), 40-7.
Effect of the anti-neoplastic drug doxorubicin on XPD-mutated DNA repair-deficient human cells
Batista LF, Artandi SE (2009). Cancer Cell, 15(6), 455-7.
Telomere uncapping, chromosomes, and carcinomas
Batista LF, Roos WP, Kaina B, Menck CF (2009). Mol Cancer Res, 7(2), 237-46.
p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal
Batista LF, Roos WP, Christmann M, Menck CF, Kaina B (2007). Cancer Res, 67(24), 11886-95.
Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks
Roos WP, Batista LF, Naumann SC, Wick W, Weller M, Menck CF, Kaina B (2007). Oncogene, 26(2), 186-97.
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine
Batista LF, Chiganças V, Brumatti G, Amarante-Mendes GP, Menck CF (2006). Apoptosis, 11(7), 1139-48.
Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells
Chiganças V, Batista LF, Brumatti G, Amarante-Mendes GP, Yasui A, Menck CF (2002). Cell Death Differ, 9(10), 1099-107.
Photorepair of RNA polymerase arrest and apoptosis after ultraviolet irradiation in normal and XPB deficient rodent cells
REVIEW ARTICLES
Chen L, Batista LFZ (2025). (Epub ahead of print). [Review]. Cold Spring Harb Perspect Biol.
Biogenesis and Regulation of Telomerase during Development and Cancer
Batista LFZ*, Dokal I*, Parker R* (*Co-Corresponding Author) (2022). [Review]. Trends Mol Med, 28, (10), 882-891.
Telomere biology disorders: time for moving towards the clinic?
Vessoni AT, Filippi-Chiela EC, Lenz G, Batista LFZ (2020). [Review]. Oncogene, 39, (10), 2055-2068.
Tumor propagating cells: drivers of tumor plasticity, heterogeneity, and recurrence
Batista LF, Artandi SE (2013). [Review]. Curr Opin Genet Dev, 23, (5), 526-33.
Understanding telomere diseases through analysis of patient-derived iPS cells
Batista LFZ, Kaina B, Meneghini R, Menck CFM (2009). [Review]. Mutat Res, 681, (2-3), 197-208.
How DNA lesions are turned into powerful killing structures: insights from UV-induced apoptosis